Source: VistaGen Therapeutics, Inc.
VistaGen Therapeutics, Inc. (OTCQB: VSTA) (VistaGen or the Company), a clinical-stage biopharmaceutical company dedicated to developing and commercializing innovative product candidates for patients with diseases and disorders involving the central nervous system (CNS), today announced that it has appointed Jerry Gin, Ph.D., MBA to its Board of Directors. Dr. Gin has also been appointed as a member of the Company's Audit Committee.
"Dr. Gin brings a myriad of
expertise in forming, building and propelling healthcare companies to
their next platforms of growth, and we believe his experience and
insight will be invaluable to VistaGen," commented Shawn Singh,
Chief Executive Officer of the Company. "We are honored to have Dr. Gin
join us as a member of our Board at such an important time for the
Company as we focus on rapidly advancing our proprietary CNS pipeline,
specifically, our lead product candidate, AV-101, through our ongoing
Phase 2a study and commence our potentially pivotal Phase 2b study in
major depressive disorder over the course of this year."
Dr. Gin has over 45 years of experience in
the healthcare industry, focusing on founding and developing
pharmaceutical, diagnostic and biotechnology companies. He is currently
the co-founder and CEO of Nuvora, Inc., a private company with a drug
delivery platform for the sustained release of ingredients through the
mouth for indications such as dry mouth, biofilm reduction and sore
throat/cough relief. Dr. Gin is also co-founder and Chairman of
Livionex, a platform technology company focused on oral care,
ophthalmology and wound care. Previously, Dr. Gin co-founded Oculex
Pharmaceuticals, which developed technology for controlled release
delivery of drugs to the interior of the eye, specifically to treat
macular edema, and served as President and CEO until it was acquired by
Allergan for $230 million. Prior to
forming Oculex, Dr. Gin co-founded and took public, ChemTrak, which
developed a home cholesterol test, commonly available in drug stores
today. Prior to ChemTrak, Dr. Gin was Director of New Business
Development and Strategic Planning for Syva, the diagnostic arm of
Syntex Pharmaceuticals, Director for Pharmaceutical and Diagnostic
businesses for Dow Chemical, and Director of BioScience Labs (now Quest
Laboratories), the clinical laboratories of Dow Chemical. For more
information on Dr. Gin, please click here.
Dr. Gin stated, "I am excited
to join the VistaGen board and believe the Company represents a very
compelling opportunity. Its lead prodrug candidate, AV-101, is
fundamentally differentiated with its ketamine-like antidepressant
effects without the undesired side effects. I believe, with the
continued development of AV-101, we have the potential to witness a
long-awaited paradigm shift in the treatment of depression and look
forward to working closely with the team to unlock the tremendous value
for patients, their families, physicians and shareholders."
VistaGen's lead oral prodrug
candidate, AV-101, is currently being evaluated in an ongoing
NIH-sponsored Phase 2a clinical study for the treatment of major
depressive disorder (MDD). The Company expects to report topline data
from the Phase 2a clinical study in the second quarter of 2017 and is
preparing to advance AV-101 into a Phase 2b MDD study in the fourth
quarter of this year.
About AV-101AV-101
(L-4-chlorokyurenine or 4-CI-KYN) is an orally-available prodrug
candidate, currently in Phase 2 development, initially for the
adjunctive treatment of MDD in patients with an inadequate response to
standard antidepressants. AV-101 has broad potential utility in other
diseases and disorders involving the CNS, including chronic neuropathic
pain and epilepsy and neurodegenerative diseases, such as Parkinson's
disease and Huntington's disease. After crossing the blood-brain barrier
and reaching brain astrocytes, AV-101 is rapidly and enzymatically
converted into 7-chlorokynurenic acid (7-Cl-KYNA), a well-characterized,
potent and selective antagonist of N-methyl-D-aspartate (NMDA)
receptors, acting by blocking the glycine-binding co-agonist site of the
NMDA receptor.
About VistaGenVistaGen
Therapeutics, Inc. is a clinical-stage biopharmaceutical company
dedicated to developing and commercializing innovative product
candidates for patients with diseases and disorders involving the CNS.
Our lead product candidate, AV-101, is a next generation, orally
available prodrug in Phase 2 development, initially for the adjunctive
treatment of MDD in patients with an inadequate response to standard
antidepressants. AV-101 is currently being evaluated in an ongoing Phase
2a clinical study being conducted by Principal Investigator, Dr. Carlos Zarate,
Chief, Section on the Neurobiology and Treatment of Mood Disorders and
Chief of Experimental Therapeutics and Pathophysiology Branch at the
National Institute of Mental Health, and Clinical Professor of
Psychiatry and Behavioral Sciences, at The George Washington University and fully funded by the U.S. National Institutes of Mental Health.
For more information, please visit www.vistagen.com and connect with the Company on Twitter, LinkedIn and Facebook.
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